The Treatment of Adult ADHD in the Context of Stimulant Use and Psychosis

Speaker Name: Dr. Nickie Mathew

Session Description:

In the adult population of those using stimulant drugs, such as methamphetamine, there is often a clinical question of how best to diagnose and treat ADHD. Also, concurrent within this population is a large percentage of people who experience psychosis. Given all of these intersecting clinical issues, this talk aims to provide practical guidance in treating this population.

Learning Objective:

  1. Understand the performance-enhancing nature of stimulant medication
  2. Understand the process of diagnosing and treating ADHD in those with substance use or psychotic disorders
  3. Understand the relationship between stimulants and psychosis
  4. Understand how to treat psychosis in those with stimulant use disorder

References:

Margaret H. Sibley (2021). Empirically-informed guidelines for first-time adult ADHD diagnosis, Journal of Clinical and Experimental Neuropsychology, 43:4, 340-351, DOI: 10.1080/13803395.2021.1923665

Shirai T, Okazaki S, Tanifuji T, Otsuka I, Horai T, Mouri K, Takemura Y, Aso K, Yamamoto N, Hishimoto A. Epigenome-wide association study on methamphetamine dependence. Addict Biol. 2024 Mar;29(3):e13383.

doi: 10.1111/adb.13383

Moran, L. V., Ongur, D., Hsu, J., Castro, V. M., Perlis, R. H., & Schneeweiss, S. (2019). Psychosis with methylphenidate or amphetamine in patients with ADHD. New England Journal of Medicine, 380(12), 1128-1138.

BIO

Dr. Mathew completed an addiction psychiatry fellowship at Yale University and a forensic psychiatry fellowship at the University of British Columbia. He is a Clinical Professor at the University of British Columbia. He is currently serving as the medical director for complex concurrent disorders at the Provincial Health Services Authority.